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Reversing Plaque? Why Heart Disease Is Actually Metabolic | Dr Anthony Jay
09 September 2026

Reversing Plaque? Why Heart Disease Is Actually Metabolic | Dr Anthony Jay

The Evolving Wellness Podcast with Sarah Kleiner Wellness

About

On the Evolving Wellness podcast, host Sarah interviews returning guest Dr. Anthony Jay (PhD biochemistry; former Mayo Clinic researcher) about his book Sugar Beat: How Sugar, Not Cholesterol, Destroys Arteries and his broader critique of mainstream cardiology. Jay cites a 28,000-person study where insulin resistance had the highest heart-attack hazard ratio (6.4) versus hypertension (2.2), triglycerides (2.1), and LDL (1.38), arguing doctors overemphasize cholesterol while neglecting insulin and HOMA-IR. He claims statins increase arterial calcification and diabetes risk, criticizes organizations like the American Heart Association, and disputes fears around LDL, ApoB, and Lp(a), describing them as fat-transport/oxidation-related. Jay recommends focusing on metabolic health, diet and fasting to promote fat burning and plaque reversal, cautions about processed foods and mislabeled oils, discusses CAC vs CCTA imaging variability, and notes genetic nuances such as iron-related risk and sitosterolemia.


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Connect with Dr. Anthony Jay

website - https://www.ajconsultingcompany.com/

YT - https://www.youtube.com/@dranthonyjay 


Books:

Sugar Beat - https://amzlink.to/az0hIdy8AMV03

Estrogeneration:  https://amzlink.to/az0U0rLUAUr8f


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Timestamp:

00:00 Insulin Resistance vs LDL

01:05 Meet Dr Anthony Jay

04:03 Censorship and Free Speech

10:14 Seed Oils and Food Fraud

14:04 Statins and Calcified Plaque

21:53 Sugar Beat Heart Disease Mechanism

30:59 Saturated Fat Genes and Lp a

40:52 Sleep Stress Insulin Link

42:14 Metabolic Flexibility Basics

42:55 Genetic High Cholesterol Cases

43:40 Oreo Study LDL Trap

45:45 Statins Guidelines Corruption

51:02 CAC vs CCTA Scans

57:04 Labs Genes Wrap Up

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This video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!

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