#519 Mild Autonomous Cortisol Secretion
30 March 2026

#519 Mild Autonomous Cortisol Secretion

The Curbsiders Internal Medicine Podcast

About

Become a master of cortisol and learn how to identify and treat a common condition in patients with adrenal tumors! Join us as we learn about mild autonomous cortisol secretion (MACS) with Dr. Irina Bancos (@irinabancos), an internationally renowned adrenal expert!

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Show Segments


    Intro
    Advice for listeners
    Adrenal incidentaloma Definition (Case 1)
    Hormonal workup for adrenal incidentalomas
    Defining mild autonomous cortisol secretion (MACS)
    Significance and prevalence of MACS
    Diagnostic testing for MACS
    Treatment options for MACS (surgery vs. comorbidity management)
    Post surgical management of MACS (Case 2)
    Diagnostic testing for adrenal insufficiency (AI)
    Glucocorticoid withdrawal syndrome management
    Deciding when patients are able to come off of steroids after AI
    Outcomes after adrenalectomy in MACS
    Take home points


Credits

Written and produced by Paul Wurtz MD. Show notes, cover art, and infographic also created by Paul Wurtz MD.


    Producer, writer, show notes, and CME: Mobeen Ahmad MD
    Cover art and infographic: Kate Grant MBChb, MRCGP
    Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP; Mobeen Ahmad MD
    Reviewer: Emi Okamoto MD
    Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
    Technical Production: PodPaste
    Guest: Irina Bancos MD, MSc


Disclosures

Dr. Bancos has the following disclosures:

    Consulting, advisory board or safety monitoring board (all fees to institution): Recordati, Corcept, Esteve, Spruce, Sparrow, Diurnal, Neurocrine, Lufordi, Adaptyx, Crinetics, Xeris, AstraZeneca, NovoNordisc, Camurus.
    Research grant for investigator initiated research (to institution): Esteve, Recordati


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