The Roots of Borderline Personality Disorder - Inflammation & Oxidative Stress
06 September 2025

The Roots of Borderline Personality Disorder - Inflammation & Oxidative Stress

Psychiatry and Depth Psychology – with Dr. Valentin Rădoi

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In this episode, we delve into the biological roots of Borderline Personality Disorder (BPD), investigating the role of inflammation and oxidative stress in the emotional intensity and instability characteristic of this condition.For the full written version of this material, as well as an youtube video on this topic, visit my website: https://www.drvalentinradoi.com/resurse-educaionale-1We go deeper into the science behind BPD, exploring how chronic inflammation in the body and brain, along with an imbalance known as oxidative stress, can affect the brain circuits responsible for emotional regulation. We will discuss how these physiological processes can disrupt the function of key neurotransmitters, leading to the intense mood swings and impulsivity often seen in BPD.Through the story of "Ana," we'll illustrate how these biological factors can manifest in daily life, showing how a state of constant physiological stress can amplify emotional reactions and impact relationships, self-image, and overall well-being. Ana's journey highlights that these invisible biological battles are a real part of the challenges faced in BPD.This conversation delivers a crucial message: your biology is not your destiny. While inflammation and oxidative stress can create a predisposition for emotional dysregulation, understanding these mechanisms opens new paths to healing. By addressing these physiological factors, you can support your brain's health, learn to manage your emotional sensitivity, and build a more resilient and fulfilling life.