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Dr. Chris Palmer: Your Diet Could Be Causing Anxiety, Depression & Brain Fog (6 Simple Changes to Make Today)
03 July 2026

Dr. Chris Palmer: Your Diet Could Be Causing Anxiety, Depression & Brain Fog (6 Simple Changes to Make Today)

On Purpose with Jay Shetty

About
What if we've been thinking about mental illness all wrong? Harvard psychiatrist Dr. Chris Palmer argues that conditions like anxiety, depression, bipolar disorder, and schizophrenia may be rooted in metabolic dysfunction, not just genetics or trauma. Drawing on decades of clinical research, he explains which chemical additives may be harming our brains, why ketogenic diets are showing remarkable promise for severe mental illness, and why recovery is about far more than willpower. Chris also opens up to Jay about the deeply personal story of his mother that inspired him to pursue psychiatry, and why, despite the growing mental health crisis, he remains genuinely hopeful for the next generation.
In this episode you'll learn:
How to Recognize the Connection Between Diet & Mental Health 
How to Notice Warning Signs of Metabolic Dysfunction 
How to Support Loved Ones Through a Mental Health Crisis  
How to Become More Resilient with Self-Care  
How to Turn Personal Pain Into Purpose 
How to Use Fasting & Ketogenic Diets Safely 
How to Talk to Kids About Nutrition & Brain Health 
Healing rarely comes from one single fix. Instead it comes from understanding the whole person: body, brain, and everything we feed both. Sometimes the most radical form of self-love is simply asking what’s going into your body, and why? 
With Love and Gratitude,
Jay Shetty
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What We Discuss:
00:00 Intro
00:22 The Chronic Disease Epidemic
01:54 The Link Between Mental Health and Diet 
05:17 What Metabolism Really Means 
07:57 The Shocking Chemicals Added to Food
09:55 Why Is The Food System In America So Harmful? 
14:45 The Impact of Ultra Processed Foods on Mental Health   
16:29 Why Your Brain Actually Needs Certain Foods 
17:21 Brain Fog, Depression, Anxiety & Burnout
18:46 Building Mental Resilience 
21:48 Self Care Will Improve Your Brain Functioning
23:57 The “Make America Healthy Again” Movement 
25:25 The Next Era of Healthcare in America 
27:45 A Healthy vs Unhealthy Metabolism 
28:30 Warning Signs From Your Metabolism  
29:13 93% of Americans Have Abnormal Biomarkers 
30:00 6 Steps For Healing Your Metabolism 
31:11 The Truth About Alcohol, Weed & Vaping 
35:46 Exercise Doesn't Have to Be Extreme to be Effective 
36:30 Stop Looking at Screens All Day!
37:10 Why No Single Diet Works for Everyone
38:45 The Power of Eating More Whole Foods 
39:45 Do You Know What Your Body Needs?  
40:20 What Are Nutrient Dense Foods? 
41:17 Why Some People Are Metabolically Compromised 
42:22 Dietary Intervention
44:00 The Ancient Power of Fasting
46:17 Why Bipolar Diagnoses Are Rising
50:08 When Medication Isn't Enough
51:24 How a Ketogenic Diet Can Impact Bipolar Disorder
53:06 The History of The Ketogenic Diet (It’s Not What You Think) 
54:50 How The Ketogenic Diet Can Stop Seizures 
56:20 The Power of Healing 
57:47 The Unexpected Grief of Getting Better
59:05 A Life Dedicated to Psychiatry  
1:04:15 Keeping a Healthy Dose of Skepticism 
1:05:30 Rethinking New Treatments 
1:06:55 Advice for Concerned Parents
1:07:31 What Are Epigenetics? 
1:11:23 The Worst Chemicals For Brain Health 
1:13:30 This Is An Ethics Issue…
1:14:09 Which Chemicals Cause Generational Anxiety? 
1:18:20 Dr. Chris Palmer on Final Five
Episode Resources:
Read | Brain Energy 
Website | https://www.chrispalmermd.com/ 
YouTube | https://www.youtube.com/@ChrisPalmerMD 
Facebook | https://www.facebook.com/ChrisPalmerMD/ 
Instagram | https://www.instagram.com/chrispalmermd/ 
X | https://x.com/ChrisPalmerMD/
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