The Dark Side of Human Optimisation: Nicotine, Peptides, NAD+ & the Enhanced Games | Longevity Doctor Explains

This week I'm joined by Dr Jack Kreindler, physician, healthtech entrepreneur and founder of WellFounded Health and the Centre for Health and Human Performance, and someone who has spent 26 years asking one of the most important questions in medicine, what does it mean to not just fix disease, but to truly enhance human life?

We explore longevity, prevention, performance and what the most advanced medicine in the world is learning about how to live well for longer.

Dr Jack Kreindler qualified in medicine and physiology from University College London and spent a decade as an emergency physician before founding the Centre for Health and Human Performance in Harley Street in 2007. He is an honorary clinical research fellow at Imperial College London, founder and CEO of WellFounded Health and a leading voice on healthy longevity, human performance and the future of medicine. He has worked with elite athletes, extreme environment explorers and high performance executives across the world.

What we explore together:

Why medicine is shifting from fixing disease to enhancing physiology and what that means for you

What burning the candle at three ends is actually doing to your brain and body

Why cadence is king and how everything in nature and biology moves in waves

What the most advanced health testing actually looks like and what it tells us

The truth about longevity supplements, peptides and biohacking and who they actually work for

Why your history is still the most powerful diagnostic tool ever invented

What it really means to enhance a human life rather than just extend it

Love, Sarah Ann 💛

My book 'Healthy Shouldn't Be This Hard': https://www.amazon.co.uk/Healthy-Shouldnt-Be-This-Hard-ebook/dp/B0G1DHNRV5

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Chapters

00:00 Introduction

02:59 How Jack's view of medicine changed over 26 years

05:58 Burning the candle at three ends and what it costs you

09:04 Why cadence is king in biology and life

12:00 What a prevention first approach to health looks like

18:00 Your history from one cell to 38 trillion

21:02 What advanced health testing actually reveals

30:00 Hormones, menopause and andropause

33:02 Cardiovascular risk and how to assess it properly

36:00 Brain health, dementia risk and what you can do now

39:07 The gut microbiome and its role in everything

42:00 Extreme environments and what they teach us about health

45:08 Elite sport science applied to everyday health

48:00 The longevity space and what the evidence actually shows

51:07 Peptides, supplements and biohacking

54:06 What works, what doesn't and how to know the difference

57:07 AI and the future of personalised medicine

66:04 The bell shaped curve and why nothing works for everyone

69:08 What enhancing a human life really means

72:00 Not dying dull and what Jack has learned

75:02 Final thoughts on living well and being well