453: Elizabeth Perkins Says Working with Dan Levy and Old Friend Laurie Metcalf on Netflix’s Big Mistakes Has Been “a Gift”

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Actress Elizabeth Perkins continues to balance a prolific career with a grounded personal life, bringing decades of experience to a new wave of roles. She sat down with LifeMinute editor-in-chief Joann Butler to discuss her latest projects and the perspective she’s gained throughout a career that’s still going strong.

Perkins stars in Netflix’s Big Mistakes, a dark comedy from Dan Levy and Rachel Sennott, about siblings pulled into organized crime. She praised Levy’s inclusive, collaborative style, calling the set environment both rare and inspiring—made even more special by finally working with her longtime friend, Laurie Metcalf.

She’s also set to appear in FX’s Cry Wolf, from Sarah Treem, alongside Olivia Colman and Brie Larson, tackling the complexities of Child Protective Services. She also had a brief, but impactful appearance in The Housemaid, directed by Paul Feig, continuing a run of high-profile collaborations. 

With a career spanning film, television, and theater, Perkins has built an eclectic résumé. She earned multiple award nominations for her role on Weeds and won a Gracie Award for Sharp Objects. Her early breakout came in Big alongside Tom Hanks, with other notable performances in About Last Night with Demi Moore and Rob Lowe, Avalon, and a wide range of film and television projects that showcase her versatility. 

Off-screen, Perkins finds balance in a quieter life spent hiking, making collage art, and connecting with nature.