03 August 2026
The New Science of Healthy Aging: 5 Biomarkers That Predict How Well You'll Age | Florence Comite
High Performance Health
About
Longevity expert Dr Florence Comite joins me to explain why testosterone, not estrogen, drives body composition and ageing in midlife women.
Decline isn't inevitable, it's programmable.
She unpacks why low testosterone is likely behind your belly fat, brain fog and low energy from your 30s on, why only a third of us should fast, and the five biomarkers your doctor probably isn't checking fasting glucose, HbA1c, fasting insulin, cholesterol risk ratio and free testosterone that predict where your health span is headed.
WHAT YOU'LL LEARN
- Why testosterone (which women carry in larger amounts than estrogen) starts declining in your 30s - and how its fall drives the belly fat, brain fog and low energy that leave you feeling not like yourself
- What "I don't feel like myself anymore" is actually signaling beneath the surface
- How cortisol quietly drives the anxiety-out-of-nowhere, the 2am wake-ups and the stubborn weight around your middle
- Why only a third of women should fast, and the 3-hour glucose test that tells you which third you're in
- The five biomarkers your doctor probably isn't checking, and what they reveal about your risk of diabetes, heart disease and where your health span is headed
TIMESTAMPS
00:00 Intro: Why You Don't Feel Like Yourself After 35 - Peak Health, Testosterone Decline & the 30s Shift
05:52 - Perimenopause, Cortisol & Anxiety Out of Nowhere: Belly Fat, Sleep and the Caregiver Load
13:28 - Wearables, CGM & the Fasting Third/Third/Third: Measuring How Your Body Really Ages
20:11 - Who Should Actually Fast: The 3-Hour Glucose Test, Protein at Every Meal & the Oatmeal Trap
27:00 - Testosterone for Body Composition & Energy: UK Access, the 2024 Study & Protein for Muscle
33:46 - The 5 Biomarkers That Predict How You Age - Plus the 7 Patterns of Health Decline
39:37 - Decade by Decade for Women vs Men: Bone Loss, Osteoporosis, Andropause & Owning Your Healthspan
VALUABLE RESOURCES
- Invincible (Dr Comite's new book): https://www.penguin.co.uk/books/475986/invincible-by-comite-florence/9781529977066
- Dr Florence Comite's website: https://www.comitemd.com/
- Follow Dr Comite on Instagram: https://www.instagram.com/drflorencecomite/
AlgaeCal Plus*‡: Science-backed supplements designed to support healthy aging👉 http://algaecal.info/angela-foster
*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
‡Results consistent with clinical trials. Individual results vs clinical results may vary.
ABOUT THE GUEST
Dr Florence Comite is a clinician-scientist, endocrinologist and global authority on healthy longevity, and founder of the Comite Center for Precision Medicine & Healthy Longevity in New York, Palo Alto and Miami Beach. Known for her Nof1™ precision approach, built on hormones, metabolism and wearable data, she helps patients detect, predict and reverse biological ageing. She's a New York Times bestselling author, most recently of Invincible: Defy Your Genetic Destiny to Live Better, Longer.
Want to go deeper? Start here:
Take the BioSyncing Quiz to help you understand what’s actually happening in your body — and how to fix it.
👉 https://biosyncing.scoreapp.com
🌸Reset your hormones, restore your energy, and reconnect with your body in just 21 days.
👉 https://www.highperformance-health.com
💌 Fresh Start Sundays Newsletter
Your weekly 3-minute guide to creating the healthiest, most vibrant version of you.
Each Monday, get one simple habit to boost energy, balance hormones, and enhance longevity - joined by 25,000+ women worldwide.
👉 https://angelafosterperformance.com/
🥗 The Ultimate Guide to Creatine for Women
👉 https://academy.angelafosterperformance.com/creatine-guide
⚡ 10 Habits That Helped Me Reverse My Biological Age by 25 Years During Perimenopause
👉 https://academy.angelafosterperformance.com/10-habits-optin-page
👩💼 About Angela Foster
Angela Foster is a corporate lawyer turned health and performance coach, keynote speaker, and creator of the BioSyncing® Method. She is the host of the High Performance Health Podcast, featuring over 500 conversations with world-leading experts in longevity, hormones, neuroscience, nutrition, and female performance.
Angela's mission is to help one million ambitious women optimise their hormones, energy, cognitive performance, and longevity, so they never have to choose between success and their health.
If you enjoyed this episode, please subscribe, leave a review, and share it with someone who would benefit from it.
Follow me for daily health and performance tips:
Instagram: https://www.instagram.com/angelasfoster/
Facebook: https://www.facebook.com/AngelaFosterPerformance
#AngelaFoster #HighPerformanceHealth #Longevity #HealthyAgeing
Decline isn't inevitable, it's programmable.
She unpacks why low testosterone is likely behind your belly fat, brain fog and low energy from your 30s on, why only a third of us should fast, and the five biomarkers your doctor probably isn't checking fasting glucose, HbA1c, fasting insulin, cholesterol risk ratio and free testosterone that predict where your health span is headed.
WHAT YOU'LL LEARN
- Why testosterone (which women carry in larger amounts than estrogen) starts declining in your 30s - and how its fall drives the belly fat, brain fog and low energy that leave you feeling not like yourself
- What "I don't feel like myself anymore" is actually signaling beneath the surface
- How cortisol quietly drives the anxiety-out-of-nowhere, the 2am wake-ups and the stubborn weight around your middle
- Why only a third of women should fast, and the 3-hour glucose test that tells you which third you're in
- The five biomarkers your doctor probably isn't checking, and what they reveal about your risk of diabetes, heart disease and where your health span is headed
TIMESTAMPS
00:00 Intro: Why You Don't Feel Like Yourself After 35 - Peak Health, Testosterone Decline & the 30s Shift
05:52 - Perimenopause, Cortisol & Anxiety Out of Nowhere: Belly Fat, Sleep and the Caregiver Load
13:28 - Wearables, CGM & the Fasting Third/Third/Third: Measuring How Your Body Really Ages
20:11 - Who Should Actually Fast: The 3-Hour Glucose Test, Protein at Every Meal & the Oatmeal Trap
27:00 - Testosterone for Body Composition & Energy: UK Access, the 2024 Study & Protein for Muscle
33:46 - The 5 Biomarkers That Predict How You Age - Plus the 7 Patterns of Health Decline
39:37 - Decade by Decade for Women vs Men: Bone Loss, Osteoporosis, Andropause & Owning Your Healthspan
VALUABLE RESOURCES
- Invincible (Dr Comite's new book): https://www.penguin.co.uk/books/475986/invincible-by-comite-florence/9781529977066
- Dr Florence Comite's website: https://www.comitemd.com/
- Follow Dr Comite on Instagram: https://www.instagram.com/drflorencecomite/
AlgaeCal Plus*‡: Science-backed supplements designed to support healthy aging👉 http://algaecal.info/angela-foster
*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
‡Results consistent with clinical trials. Individual results vs clinical results may vary.
ABOUT THE GUEST
Dr Florence Comite is a clinician-scientist, endocrinologist and global authority on healthy longevity, and founder of the Comite Center for Precision Medicine & Healthy Longevity in New York, Palo Alto and Miami Beach. Known for her Nof1™ precision approach, built on hormones, metabolism and wearable data, she helps patients detect, predict and reverse biological ageing. She's a New York Times bestselling author, most recently of Invincible: Defy Your Genetic Destiny to Live Better, Longer.
Want to go deeper? Start here:
Take the BioSyncing Quiz to help you understand what’s actually happening in your body — and how to fix it.
👉 https://biosyncing.scoreapp.com
🌸Reset your hormones, restore your energy, and reconnect with your body in just 21 days.
👉 https://www.highperformance-health.com
💌 Fresh Start Sundays Newsletter
Your weekly 3-minute guide to creating the healthiest, most vibrant version of you.
Each Monday, get one simple habit to boost energy, balance hormones, and enhance longevity - joined by 25,000+ women worldwide.
👉 https://angelafosterperformance.com/
🥗 The Ultimate Guide to Creatine for Women
👉 https://academy.angelafosterperformance.com/creatine-guide
⚡ 10 Habits That Helped Me Reverse My Biological Age by 25 Years During Perimenopause
👉 https://academy.angelafosterperformance.com/10-habits-optin-page
👩💼 About Angela Foster
Angela Foster is a corporate lawyer turned health and performance coach, keynote speaker, and creator of the BioSyncing® Method. She is the host of the High Performance Health Podcast, featuring over 500 conversations with world-leading experts in longevity, hormones, neuroscience, nutrition, and female performance.
Angela's mission is to help one million ambitious women optimise their hormones, energy, cognitive performance, and longevity, so they never have to choose between success and their health.
If you enjoyed this episode, please subscribe, leave a review, and share it with someone who would benefit from it.
Follow me for daily health and performance tips:
Instagram: https://www.instagram.com/angelasfoster/
Facebook: https://www.facebook.com/AngelaFosterPerformance
#AngelaFoster #HighPerformanceHealth #Longevity #HealthyAgeing