H5N1 Avian Flu Spreads Globally in 2025: Thousands of Bird Deaths, Hundreds of Human Cases Reported Worldwide
29 August 2025

H5N1 Avian Flu Spreads Globally in 2025: Thousands of Bird Deaths, Hundreds of Human Cases Reported Worldwide

H5N1 Global Scan: Avian Flu Worldwide

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You’re listening to H5N1 Global Scan: Avian Flu Worldwide, your international focus from Quiet Please. Today’s episode examines the ongoing global impact of the H5N1 avian flu in 2025.

Since 2020, highly pathogenic H5N1 outbreaks have reached almost every continent except Australia. According to the World Health Organization, as of July 2025, there have been nearly 1,000 reported human cases and hundreds of deaths worldwide, with most infections caused by animal-to-human transmission. The Americas, Europe, Asia, and Africa have all faced significant animal outbreaks, resulting in unprecedented fatalities among wild birds and poultry. For example, from January to August 2025, the United States recorded over a hundred avian influenza outbreaks across thirty-two states, Peru reported new poultry cases, and Mexico confirmed its first human infection in a young child. Africa and Europe continue to see H5N1 spread among both domestic flocks and wild bird populations, with recent clusters reported in the United Kingdom and Mediterranean countries.

WHO and the Food and Agriculture Organization have emphasized global coordination, urging member states to step up surveillance and report all animal and human cases promptly. They assess the current public risk as low but advise caution for people with occupational exposure, like farm workers. The Pan American Health Organization underscores the ongoing risk in the Americas, highlighting the rapid southward spread through migratory flyways and increased animal-to-human spillover.

Cross-border animal movement and the global poultry trade remain challenging. Stringent controls in some regions, such as mass culls following outbreaks, have stabilized poultry exports in Europe but contributed to egg and poultry meat shortages in North America and Asia. According to Wikipedia’s summary of recent years, the United States alone culled over 20 million chickens in late 2024, severely impacting the food supply. Several countries, including India, Cambodia, and Mexico, have also recorded fatal human cases following direct contact with infected birds.

International research initiatives are focused on the changing genetics of the virus as it spreads among mammals and birds. The Centers for Disease Control and Prevention and EU health agencies are monitoring for signs of increased human-to-human transmission or viral mutations that could elevate pandemic risk.

Vaccine development is at the forefront of the global response. The United States, European Union, and China have accelerated clinical trials for new and updated avian influenza vaccines designed to protect both poultry flocks and humans at risk. However, distribution remains uneven. The FAO stresses the importance of equitable access, particularly in lower-income regions facing rising outbreaks.

Different national approaches show wide variation. China maintains aggressive culling and live-poultry market closures, while some European countries focus on surveillance and rapid vaccinations in at-risk zones. Southeast Asia prioritizes community awareness and rapid case identification, whereas North America has ramped up monitoring of both livestock and humans, increasing testing and preparedness drills.

Thank you for tuning in to H5N1 Global Scan: Avian Flu Worldwide. Stay safe, stay informed, and join us next week as we continue to cover the most urgent public health stories from around the world. This has been a Quiet Please production. For more, check out Quiet Please Dot A I.

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