Buprenorphine Deep Dive: Neuroscience, Safety, and Clinical Decision-Making
18 March 2026

Buprenorphine Deep Dive: Neuroscience, Safety, and Clinical Decision-Making

Drug Diversion Insights with Terri Vidals

About

In this episode of Drug Diversion Insights, Terri sits down with Dr. Don Teater, a leading expert in pain management and addiction medicine, for a deeper exploration of buprenorphine—through both a clinical and neuroscience lens.

Together, they unpack what happens in the brain after opioid exposure and how those changes shape treatment decisions for patients with and without substance use disorder.

This conversation tackles some of the most complex and practical questions in addiction medicine, including:

• How opioid exposure alters brain function over time
• Differences in response between individuals with and without substance use disorder
• When to consider abstinence-based treatment vs. buprenorphine
• Whether healthcare professionals can safely return to work while on buprenorphine
• Considerations after completing abstinence-based recovery

They also explore emerging research on buprenorphine in postoperative pain management, including its safety advantages and the challenges clinicians face with dosing and efficacy in high-tolerance patients.

This is a nuanced, evidence-based discussion designed for clinicians, pharmacy leaders, opioid stewardship teams, and healthcare decision-makers navigating complex treatment and policy decisions.



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