Gut Metabolites and the Brain: What Autism Research Is Revealing
08 April 2026

Gut Metabolites and the Brain: What Autism Research Is Revealing

Demystifying PANS/PANDAS Podcast

About

The biggest driver of brain symptoms might be what’s happening in the gut. In this episode of Demystifying PANS/PANDAS, we are joined by Dr. James Adams to talk about microbial metabolites, hidden yeast and bacterial issues in autism, a new urine-based metabolite test, and why microbiota transplant therapy may improve mood, sleep, and behavior by restoring microbial balance.

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About the Guest:

Dr. James Adams is a professor at Arizona State University and a leader in its autism research program, with decades of work focused on identifying biological contributors to autism and advancing evidence-based interventions. His path into the field began after his daughter was diagnosed with severe autism and intellectual disability, motivating his pursuit of research aimed at understanding root causes rather than managing symptoms alone.

His research explores gut dysbiosis, yeast and bacterial overgrowth, microbial metabolites, and microbiota transplant therapy, with ongoing efforts to develop practical diagnostic tools and refine treatment approaches through clinical studies.

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Social Handles:

Website: http://www.adamsautismresearch.com/

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Nancy O’Hara, MD, MPH, FAAP, FMAPS

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