a16z Podcast

a16z Podcast

Andreessen Horowitz

a16z Podcast

Entrepreneurship Technology Science English

The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

Where Crypto Meets AI with Chris Dixon & David George

Where Crypto Meets AI with Chris Dixon & David George

What happens when two of the biggest tech waves—AI and crypto—start to converge?In this LP Summit conversation, a16z General Partners Chris Dixon and David George explore how stablecoins are creating a new global financial layer, why generative AI is reshaping market structures, and how the next tech giants will be built.From network effects to native AI business models, this is a sharp look at...

Rick Rubin: Vibe Coding is the Punk Rock of Software

Rick Rubin: Vibe Coding is the Punk Rock of Software

In this episode a16z co-founders Marc Andreessen and Ben Horowitz sit down with legendary music producer and bestselling author Rick Rubin to explore the origin of his unexpected new creation: "The Way of Code"*Blending ancient philosophy and modern AI, The Way of Code reimagines the 3,000-year-old Tao Te Ching for the age of artificial intelligence, software, and “vibe coding.” What began as a...

Where Value Will Accrue in AI: Martin Casado & Sarah Wang

Where Value Will Accrue in AI: Martin Casado & Sarah Wang

AI’s breakout moment is here - but where is the real value accruing, and what’s just hype?Recorded live at a16z’s annual LP Summit, General Partners Erik Torenberg, Martin Casado, and Sarah Wang unpack the current state of play in AI. From the myth of the GPT wrapper to the rapid rise of apps like Cursor, the conversation explores where defensibility is emerging, how platform shifts mirror (and...

Sovereign AI: Why Nations Are Building Their Own Models

Sovereign AI: Why Nations Are Building Their Own Models

What happens when AI stops being just infrastructure—and becomes a matter of national identity and global power?In this episode, a16z’s Anjney Midha and Guido Appenzeller explore the rise of sovereign AI—the idea that countries must own their own AI models, data centers, and value systems.From Saudi Arabia’s $100B+ AI ambitions to the cultural stakes of model alignment, we examine:Why nations are...

What Is an AI Agent?

What Is an AI Agent?

What exactly is an AI agent — and does anyone actually agree?In this episode, taken from of AI + a16z, General Partner Guido Appenzeller and partners Matt Bornstein and Yoko Li break down one of the most hyped- and most hotly debated 0 concepts in AI right now: agents.Are agents just clever wrappers around LLMs? Tools that can reason and act? Or simply a fresh label for familiar tech?Whether...

The Evolution of the Firm — with Ben and Marc

The Evolution of the Firm — with Ben and Marc

Recorded live at the 2025 a16z LP Summit, this episode is a candid conversation between a16z cofounders Marc Andreessen and Ben Horowitz—hosted by general partner Erik Torenberg.They cover the evolution of a16z from startup firm to multi-practice platform, how the media landscape is shaped by meme-speed narratives, why reorgs—not just returns—determine who wins, and what it takes to build an...

Unbundling the BPO: How AI Is Disrupting Outsourced Work

Unbundling the BPO: How AI Is Disrupting Outsourced Work

Business Process Outsourcing (BPO) is a $300 billion industry powering the back- and front-office operations of the world’s largest companies.In her article, "Unbundling the BPO: How AI Will Disrupt Outsourced Work," Kimberly Tan (Partner, a16z) explores how the rise of AI is challenging the status quo. In this episode, Kimberly unpacks the shift—from call centers and invoice processing to...

Marc Andreessen: Deep Vs. Broad Founders, AI in America, & the New Face of a16z

Marc Andreessen: Deep Vs. Broad Founders, AI in America, & the New Face of a16z

Today on the a16z Podcast, we’re sharing Marc Andreessen’s recent appearance on TBPN.Marc—cofounder and general partner at a16z—joins hosts John Coogan and Jordi Hays for a wide-ranging conversation, recorded live at the a16z’s 2025 LP Conference in Las Vegas.They cover the rise of AI, the future of open source models, and how tech is transforming every corner of the economy—from education and...

What Super Agers Reveal About Preventing Disease

What Super Agers Reveal About Preventing Disease

American healthcare is in crisis—but what if we could change the system by preventing disease before it starts?In this episode of the a16z Podcast, general partner Vijay Pande sits down with Dr. Eric Topol, founder and director of the Scripps Research Translational Institute and one of the most cited researchers in medicine, to explore the cutting edge of preventive healthcare and longevity...

Startups & Defense: Katherine Boyle on TBPN

Startups & Defense: Katherine Boyle on TBPN

In this episode of th a16z Podcast, we’re sharing Katherine Boyle’s recent interview on TBPN.Katherine—General Partner at a16z and the architect of the American Dynamism thesis—joins hosts John Coogan and Jordi Hays to discuss the state of the movement today. They cover the Department of Defense’s sweeping reform efforts, the role of startups in national security, and why American Dynamism is...